Harry MacKay Harry MacKay
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Developmental Programming of Adipose Tissue Function

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One of my first projects as a masters student in Alfonso Abizaid's lab involved a rat model of postnatal over- and undernutrition. Like the work that would follow, this project was based on the developmental programming paradigm (explained in more detail here and here). Part of the 'package' that comes...
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Antioxidant Effects of Oat and Bran Compounds

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In collaboration with the the chemistry department at Carleton, I helped in conducting studies on the antioxidant effects of various compounds.  These studies combined the Abizaid lab's expertise in mouse models of obesity and metabolic function with the biochemical techniques of the chemistry department. In one study, lead by Apollinaire Tsopmo, we...
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Ghrelin Neuroendocrinology

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Some of my side projects in the Abizaid lab focused on various aspects of ghrelin signalling in the brain, and how this may mediate behavioural and metabolic adaptations to psychosocial stress and nutritional challenge. Ghrelin is a peptide hormone secreted by the stomach. It was initially thought to be a...
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Developmental Epigenetics of the Hypothalamus

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After I finished my Ph.D. in Neuroscience, I moved to Houston, Texas to join Dr. Robert Waterland’s lab at the Baylor College of Medicine as a postdoctoral fellow. The intellectual backdrop for my Ph.D. work was a concept called ‘developmental programming’, which refers to the ability for the early-life...
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Obesogenic Effects of Bisphenol-A

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Obesity seems to befall some people for no obvious reason. To be sure it runs in families, but as far as we can tell one's risk of becoming obese is at best a little more than 50% genetic. People who are obese behave differently - you can only gain...
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The Neuroscience of Concussions

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I originally made this video for the Fall 2014 session of NEUR1201 at Carleton.  I knew I would be missing one lecture due to my attendance at the Society for Neuroscience meeting that week, but I didn't want to cancel class.  This video was made in the 'sped up...
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NEUR4200: Seminar on Current Research in Neuroscience

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I taught Carleton University's advanced neuroscience seminar as a contract instructor in the Winter 2014 semester.  This course is intended for 4th year undergraduates in Carleton's Neuroscience and Mental Health program.  This course was mainly intended to develop skills in writing and presenting, as well as interpreting the scientific...
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NEUR1201: Introduction to Mental Health and Disease

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I taught four semesters of NEUR1201 from Fall 2013-Summer 2015.  This is Carleton's introductory neuroscience course, intended for students beginning the Neuroscience and Mental Health program, as well as students from other programs interested in the brain and mental health.  In addition to designing the course content (following in the...